Buddhisms and Deconstructions considers the connection between Buddhism and Derridean deconstruction, focusing on the work of Robert Magliola. Fourteen distinguished contributors discuss deconstruction and various Buddhisms—Indian, Tibetan, and Chinese —followed by an afterword in which Magliola responds directly to his critics.

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

The beginning of the journey -- What this book is about : using ideas from mathematics, economics, and physics to tackle the big questions in philosophy : what is real? what can we know? what is the difference between right and wrong? and how should we live? -- Reality and unreality -- On what there is -- Why is there something instead of nothing? the best answer I have : mathematics exists because it must and everything else exists because it (...) is made of mathematics, with an excursion into artificial intelligence -- Unfinished business -- Unfinished business from chapter two : the nature and purpose of economic models -- How Richard Dawkins got it wrong -- Why Dawkins's argument against intelligent design can't be right and a mathematical analysis of the arguments for the existence of God -- Belief -- Daydream believers -- Most beliefs are ill-considered because most false beliefs are costless to hold -- The next several chapters will explore the consequences of this observation before we return to the question of where our beliefs and knowledge come from -- Unfinished business -- Unfinished business from the preceding chapter : how color vision works, sound, and water waves, the sheer craziness of economic protectionism -- Do believers believe? -- Our ill-considered beliefs about religion : why I believe that almost nobody is deeply religious -- On what there obviously is -- Our ill-considered beliefs about free will, ESP, and life after death -- Diogenes's nightmare -- How is legitimate disagreement possible if you're arguing with someone who is as intelligent and informed as you are, shouldn't you put just as much weight on your opponent's arguments as your own? -- The fact that we persist in disagreeing is strong evidence that we don't really care what's true -- Knowledge -- Knowing your math -- Where mathematical knowledge comes from and logic and why evidence and logic are not enough -- Unfinished business -- Unfinished business from the preceding chapter : the tale of hercules and the hydra, with an excursion into the lore of very large numbers -- Incomplete thinking -- Godel's incompleteness theorem and what it doesn't say about the limits of human knowledge -- The rules of logic and the tale of a Potbellied pig -- The power of logical thought, with excursions into the most counterintuitive theorem in all of mathematics and the tale of a potbellied pig -- The rules of evidence -- What we can and can't learn from evidence, with excursions into the value of preschool and how internet porn prevents rape -- The limits to knowledge -- What physics does and doesn't tell us about what we can and cannot know -- Understanding Heisenberg's uncertainty principle -- Unfinished business -- The oddness of the quantum world and why it matters to game theorists -- Right and wrong -- Telling right from wrong -- Some hard questions about right and wrong and about life and death -- The economist's golden rule -- A rule of thumb for good behavior -- How to be socially responsible -- Putting the rule of thumb into practice -- On not being a jerk -- Goofus and gallant on immigration policy -- The economist on the playground -- Our ill-considered beliefs about fairness in the market place and in the voting booth, contrasted with our carefully considered beliefs about fairness on the playground -- Unfinished business -- How ancient talmudic scholars anticipated modern economic theory -- The life of the mind -- How to think -- Some basic rules for clear thinking, mostly about economics, but also about arithmetic, neurobiology, sin, and eschewing blather -- What to study -- Advice to college students : stay away from the English department and approach the philosophy department with caution, with an excursion into the remarkable life of Frank Ramsey. (shrink)

The say-on-pay regulation in the Dodd-Frank Act requires publicly-traded U.S. firms to hold a nonbinding, advisory shareholder vote on executive compensation. Advocates claim that SOP voting gives shareholders a mechanism to hold managers and boards more accountable. Critics contend that SOP votes may simplistically reflect shareholders’ reactions to the overall value of CEO compensation or the firm’s net income. However, based on prior research, we contend that market participants’ SOP votes are likely to consider current income attributes. For example, (...) the market punishes firms that do not meet or beat benchmarks such as analyst earnings expectations, and that shareholders scrutinize the quality of the income sources of firms that consistently meet/beat analyst expectations. We thus expect that more shareholders will provide ‘agree’ SOP votes for a firm that consistently meets/beats analyst forecasts and does so when net income does not include nonrecurring gains. Further, we consider whether perceptions about the fairness of CEO compensation play a mediating role in the relationship between the interaction of these two current income attributes and SOP votes. Results from an experiment using evening MBA students as participants indicates that the two current income attributes significantly interact with respect to the percentage of agree SOP votes, and that compensation fairness perceptions fully mediate this relationship. Further, the mediating effect of compensation fairness perceptions is robust to including CEO-level and other determinants found in prior research. We conclude with a discussion of our findings and their implications for public policy and research. (shrink)

Recently Steven E. Boër gave another turn to the discussion of the free will defence by claiming that the free will defence is irrelevant to the justification of moral evil. Conceding that free will may be of real value, Boër claims that free will could have been allowed creatures without that leading to any moral evil at all. What I shall hereafter refer to as the ‘Boër reform’ is the suggestion that God could have allowed creatures to exercise free choices (...) but have intervened with ‘coincidence miracles’ to prevent all the intended evil from actually occurring. What is important to the free will defence, according to Boër, is the ability to choose freely and not the ability to succeed in effecting what we have intended to accomplish. It is no intrusion on the freedom of our wills for God to prevent us from accomplishing what we tried to do with our free wills as long as we were free to try. (shrink)

Introduction, Thomas McLaughlinI Literature as Writing1 Representation, W. J. T. Mitchell2 Structure, John Carlos Rowe3 Writing, Barbara Johnson4 Discourse, Paul A. Bove5 Narrative, J. Hillis Miller6 Figurative Language, Thomas McLaughlin7 Performance, Henry Sayre8 Author, Donald E. PeaseII Interpretation9 Interpretation, Steven Mailloux10 Intention, Annabel Patterson11 Unconscious, Franoise Meltzer12 Determinacy/Indeterminacy, Gerald Graff13 Value/Evaluation, Barbara Herrnstein Smith14 Influence, Louis A. Renza15 Rhetoric, Stanley FishIII Literature, Culture, Politics16 Culture, Stephen Greenblatt17 Canon, John Guillory18 Literary History, Lee Patterson19 Gender, Myra Jehlen20 Race, Kwane Anthony Appiah21 (...) Ethnicity, Werner Sollors22 Ideology, James H. KavanaghIn Place of an Afterword--Someone Reading, Frank LentricchiaReferencesList of ContributorsIndex. (shrink)

Frank E. Zachos offers a comprehensive review of one of today's most important and contentious issues in biology: the species problem. After setting the stage with key background information on the topic, the book provides a brief history of species concepts from antiquity to the Modern Synthesis, followed by a discussion of the ontological status of species with a focus on the individuality thesis and potential means of reconciling it with other philosophical approaches. More than 30 different species concepts (...) found in the literature are presented in an annotated list, and the most important ones, including the Biological, Genetic, Evolutionary and different versions of the Phylogenetic Species Concept, are discussed in more detail. Specific questions addressed include the problem of asexual and prokaryotic species, intraspecific categories like subspecies and Evolutionarily Significant Units, and a potential solution to the species problem based on a hierarchical approach that distinguishes between ontological and operational species concepts. A full chapter is dedicated to the challenge of delimiting species by means of a discrete taxonomy in a continuous world of inherently fuzzy boundaries. Further, the book outlines the practical ramifications for ecology and evolutionary biology of how we define the species category, highlighting the danger of an apples and oranges problem if what we subsume under the same name ("species") is in actuality a variety of different entities. A succinct summary chapter, glossary and annotated list of references round out the coverage, making the book essential reading for all biologists looking for an accessible introduction to the historical, philosophical and practical dimensions of the species problem. (shrink)

The historical development of a field of human knowledge progresses like the solution of a jig-saw puzzle, the full extent of which is completely unknown. What begins as an ocean may become only a lake; what starts as a grove of trees may develop into a forest. As study advances through the decades, the situation is repeatedly surveyed and the interpretation of the whole is modified to accord with the added information. For these reasons, conceptions and generalizations periodically undergo alteration, (...) as effectively stated and discussed by Cooper. Universal conformity in such conceptions is of course hardly to be expected in matters that deal largely with speculation rather than with simple experimental data. (shrink)

The sociology of knowledge can most generally be defined as the discipline devoted to the social origins of thought. It is an analysis concerned with specifying the existential basis of thought, and with establishing the relationship obtained between mental structures or thought, and that existential basis. Some very interesting and difficult problems arise from this conception of the sociology of knowledge. Perhaps the most obvious of these is whether or not a sociology of knowledge, as here conceived, is theoretically possible. (...) This is a problem I do not intend to deal with at present because limitations of time prevent me from doing even partial justice to it. (shrink)

Theravāda Buddhists draw a doctrinal distinction between otherworldly (lokuttara) and this-worldly (lokiya) actions, and also an ecclesiastical distinction between bhikkhu (wandering mendicant or 4 "monastic") action and lay action. Within the Theravāda tradition these modes of action have overlapped to form a more empirically relevant set. This set is constituted by the otherworldly action of the path winning bhikkhus, the this-worldly action of ordinary bhikkhus, the path winning or bodhisatta (future Buddha) action of exceptional laymen, and the this-worldly action of (...) ordinary laymen. These four modes of action have meshed together to form the basis for very complex and persistent Theravāda societies in Sri Lanka and Southeast Asia. The article concludes with some methodological observations concerning the relationship between the study of action (as carried out in the body of the article), and the study of ethics (as carried out by most contemporary scholars in the field of religious ethics). (shrink)

Three recent research reports by Topping and Trickey, by Fair and colleagues, and by Gorard, Siddiqui and Huat See have produced data that support the conclusion that a Philosophy for Children program of one-hour-per-week structured discussions has a marked positive impact on students. This article presents data from a follow up study done three years after the completion of the study reported in Fair et al.. The data show that the positive gains in scores on the Cognitive Abilities Test were (...) still present and had not faded after three years. Given the strength of these confirmations of the positive durable impact of the P4C program of structured discussions and given the relatively low cost of implementing the P4C program, it is recommended that it become a standard part of the school curriculum. (shrink)

This study is an attempt partially to describe the sociological foundations of modern science. When the question is put, under what social circumstances did the idea of science develop, one sees that there is here an inadequately explored sociological area. Perhaps a definition and a contrast will make this clearer. By the idea of science is meant simply the proposition that the valid source of human knowledge is to be found in the analysis of experience. But knowledge in this sense (...) was not a problem in the medieval period. In the first place, it was then taken for granted that the universe was intelligible to man on the basis of divinely revealed principles. Secondly, man constituted the center of the universe, which in its entirety was thought to be subordinate to man's destiny. Thirdly, not only was the universe which existed for man then known by him, but it was endowed with human qualities. The categories of interpretation were substance, essence, form, matter, quality, and purpose. The reason why rain fell upon the earth was to grow crops; the purpose of the moon and the stars was to light the earth at night, and to act as guideposts for him on his travels. Bodies tended to their proper places, light ones upward, heavy ones earthward. Quantitative differences were inferred from these qualitative ones. It is well-known, for example, how tenaciously was the knowledge held, that heavier objects fall more quickly than lighter ones. And finally, the universe was religious. If the world existed for the benefit of man, man existed for the glory of God. Human sojourn upon the earth was merely preparation for permanent residence in eternity. (shrink)

A major problem of the philosophy of science is the construction of a comprehensive science of man and the universe. The sociology of science has a part to play in this tremendous task by indicating the extra-scientific influences bearing upon science at any given period, assisting, in this way, in developing a self-consciousness of science. It is believed that this self-consciousness is necessary to a scientific appraisal of the method of scientific inquiry, as well as being necessary to any attempt (...) to direct the development of science as an institution. This paper is to be regarded as a sociological evaluation of a work in the field of the philosophy of science, namely, F. S. C. Northrop's The Meeting of East and West. (shrink)

Positivists since the time of Comte have defined objectivity in science in terms of the absence of prejudice on the part of the scientist towards the phenomena with which he deals. It has been assumed that if the observer would contemplate the facts himself, this objectivity—an absence of bias—could be attained. However, social psychologists, notably C. H. Cooley and G. H. Mead, have shown that this is not necessarily the case. In the study of culture, an outstanding positivist, W. G. (...) Sumner, in his discussion of folkways and mores, has shown that this objectivity is impossible to attain. These men have described the process through which objects arise in one's experience, and come to be defined in terms of that experience, so that the same object may mean different things to different people. This seems to be the case with certain areas of social theory. (shrink)

The thought of Bernard Lonergan provides an epistemological position that is both true to the exigencies of modern science and yet open to the possibility of God and revealed religion. In this paper I outline Lonergan's “transcendental method,” which describes the basic pattern of operations involved in any act of human knowing, and discuss how Lonergan uses this cognitional theory as a basis for an epistemological position of critical realism. Then I explain how his approach handles some philosophical problems raised (...) by classical and modern science and show how his thought provides an intelligible link between the scientific and religious horizons. (shrink)

We have developed a process model that learns in multiple ways while finding faults in a simple control panel device. The model predicts human participants' learning through its own learning. The model's performance was systematically compared to human learning data, including the time course and specific sequence of learned behaviors. These comparisons show that the model accounts very well for measures such as problem‐solving strategy, the relative difficulty of faults, and average fault‐finding time. More important, because the model learns and (...) transfers its learning across problems, it also accounts for the faster problem‐solving times due to learning when examined across participants, across faults, and across the series of 20 trials on an individual participant basis. The model shows how learning while problem solving can lead to more recognition‐based performance, and helps explain how the shape of the learning curve can arise through learning and be modified by differential transfer. Overall, the quality of the correspondence appears to have arisen from procedural, declarative, and episodic learning all taking place within individual problem‐solving episodes. (shrink)

1. Introduction. Cultural relativity is one of the most important conceptions to which anthropology and sociology have devoted much attention in recent years. It is a theory of human conduct based upon observational studies of different cultures and different societies. Many of the leaders in the various social sciences are currently among the advocates of this viewpoint. The burden of these pages, however, is that cultural relativity is flying under false colors: it claims to be empirical but is illogical; it (...) claims to be objective but is surreptitiously moral; it claims to be reasonable but elevates irrationalism; it claims to be scientific but prevents the development of an experimental science of sociocultural conduct. These are serious charges to lodge against leading social scientists; to detail them all would require much more space than is here available. Therefore this paper will be devoted to an incomplete exposition of only two points, namely, that cultural relativity is surreptitiously moral, and, that it deprives man of rational grounds for decision in certain crucial areas. To put the matter bluntly, the advocates of cultural relativity, while they allege themselves to be scientifically amoral, sneak in through the back door a peculiarly crude form of ethnocentric morality which is clearly contrary to the observable facts of human behavior; and, while presenting a presumably scientific analysis of human conduct, leave us only with personal taste as the basis for making certain important decisions.2. Cultural Relativity Defined. Cultural relativity, briefly stated, asserts that any set of customs and institutions, or way of life, is as valid as any other. It may be well to let some representative cultural relativists speak for themselves at this point, in order to show that the summary statement of their position, just given, is correct. The author of an excellent and widely adopted textbook in cultural anthropology stresses the dignity inherent in every body of custom, and abjures us to be tolerant of the ways of other people:… cultural relativism is a philosophy which … lays stress on the dignity inherent in every body of custom, and on the need for tolerance of conventions though they may differ from one's own … the relativistic point of view brings into relief the validity of every set of norms for those people whose lives are guided by them, and the values these represent. … The very core of cultural relativism is the social discipline that comes of respect for differences—of mutual respect. Emphasis on the worth of many ways of life, not one, is an affirmation of the values of each culture. Such emphasis seeks to understand and to harmonize goals, not to judge and destroy those that do not dovetail with our own,. (shrink)

1. Introduction. The purpose of this paper is to present an initial sociological analysis of science as an institution. This kind of analysis has long been made of other aspects of culture: of the family, the state, religion, economic enterprise and the like. An institution, as the term is used here, is simply… a definite and established phase of the public mind … often seeming, on account of its permanence and the visible customs and symbols in which it is clothed, (...) to have a somewhat distinct and independent existence. (shrink)

My paper will explore boundaries and rights, the public and the private, as to the enforcement of religious legal rules in societies self-consciously founded on Islamic law. I employ as my case-study legal and social controversies aroused by the Saudi Hay’at al-amr bi-al-ma`ruf wa-al-nahy `an al-munkar, the government agency charged with “ordering the good and forbidding the evil.” The paper will first lay out some of the laws fixing the powers of the Hay’at, including various statutes issued by the king (...) but, of equal or greater importance, the received medieval fiqh rules governing the muhtasib . Focus shall be on an issue much debated in the classical law and also a long-time bone of contention in Saudi society, namely the legal limits on the powers of the Hay’at to investigate and punish immoral acts occurring in private. Limits on such powers stem from two sources, both in the law and in social understandings of that law. One source, the more prominent in public debate, concerns revelatory and fiqh and related social norms against spying or prying into people’s behavior and against undue attempts to expose people’s sins. Notably, however, this restriction affects only enforcement. The pervasiveness of laws considered to arise from the relationship of the individual to God still stands. A solitary immoral act performed in privacy can still be a sin and a crime, and punishable if it is somehow legitimately known and proved . The second source of restrictions is more far-reaching, going beyond issues of investigation and proof. As held by the majority of scholars, the Hay’at may not compel or forbid any actions for which the religious-legal ruling is under classical law a matter of legitimate difference of scholarly opinion; or inversely, the Hay’at may compel or forbid only those actions as to which there is a divine command known to a certainty either from a revealed text or from the consensus of scholars. A commonly noted abuse by the Hay’at in Saudi Arabia has been to attempt to enforce rules lacking requisite certainty, such as requiring veiling of the face. Rules known to a certainty have a pervasive role in Islamic constitutional theory. In principle, such rules must be enforced, regardless of whether they concern matters other societies may consider individual or private, such as changing one’s religion. Rules lacking that high degree of certainty cannot – without separate justification on grounds other than religious text – define sins or crimes or be enforced as general rules by the state. Though seemingly scholastic and philosophical, this restriction is potentially crucial in defining a realm of individual autonomy in religious matters and shaping the boundary between public and private in societies self-consciously founded in Islamic law. It is important to examine to what extent the restriction is reflected in legal and social practice in such societies. (shrink)

Operationism may tentatively be defined as that scientific method which defines its concepts in terms of observable or communicable operations, however carried out. With few exceptions, it has been put forward as representing positivism in contemporary sociology. Sellars refers to it as a new and virulent form of positivism—logical positivism. In philosophy, logical positivism is the culmination of the sensationalism of Berkeley and Hume, the positivism of Mach and Avenarius and Comte, and the logistic of Russell and Wittgenstein. In sociology, (...) the philosophic assumptions of this school have been stated in a naive form, in addition to presenting Kantian idealism contradicted by an assumption of philosophic realism. (shrink)